多个系统缩的声乐:帕金森症类型的现象?
Michela J Mir1, Nicole E Herndon2,3, Aparna Wagle Shukla3,4
1Department of Physical Therapy, BREATHE Center, University of Florida, Gainesville, Florida, USA.
Movement disorders clinical practice
|February 5, 2024
概括
语音,一个语音特征,可能有助于区分多系统性缩-帕金森型 (MSA-P) 和帕金森病. 这一发现有助于早期诊断和适当管理MSA-P患者.
科学领域:
- 神经学 神经学
- 语言病理学 语音病理学
背景情况:
- 多系统性缩 (MSA) 与帕金森病 (PD) 的早期症状相同,使诊断复杂化.
- 区分MSA和帕金森症对于及时有效的治疗计划至关重要.
研究的目的:
- 作为MSA-帕金森型 (MSA-P) 的潜在区分临床标志物,研究声拍.
主要方法:
- 一系列病例详细介绍了三名被诊断患有MSA-P的人的临床病史.
- 在所有参与者的神经学和运动语音评估中发现了声乐.
主要成果:
- 在MSA-P.的个体中观察到声拍,其特点是声调和声音强度在发音过程中的波动,在MSA-P.的个体中观察到.
- 这种语言特征可能源于MSA-P中常见的一般化喉功能障碍.
结论:
- 语音声可以作为MSA-P的独特语音标记.
- 建议通过声学和感知语音分析进行进一步的研究,以验证这些发现与PD和其他MSA变体相对应.
相关概念视频
Parkinson's Disease: Overview
547
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
547
Parkinson's Disease: Treatment
268
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
268
Respiratory System Abnormal Finding II: Palpation and Auscultation
466
In assessing respiratory abnormalities, palpation and auscultation are critical tools for detecting and interpreting various pathophysiological changes. These techniques provide insight into underlying disorders by evaluating tactile sensations and sounds produced by the respiratory system.
Palpation Findings
During a respiratory assessment, palpation can reveal several vital abnormalities:
Palpation Findings
During a respiratory assessment, palpation can reveal several vital abnormalities:
466
Neural Regulation
39.4K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
39.4K
Muscle Stimulation Frequency
2.2K
The contraction strength of muscles is regulated by motor neurons, which modulate the frequency of action potentials dispatched to the motor units based on the body's requirements. This process of varying the muscle stimulation frequency allows muscles to contract with a force that is precisely tailored to the needs of the moment, whether lifting a feather or a heavy box.
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
2.2K
Cardiovascular System Abnormal Findings II: Auscultation
150
Auscultation, an essential part of a heart examination, is done using a stethoscope. It provides crucial information about heart function and possible heart problems. Due to heart problems, abnormal sounds can be heard during systole or diastole. These sounds include S3 and S4 gallops, opening snaps, systolic clicks, and murmurs.
Abnormal Heart Sounds
Gallops:
Abnormal Heart Sounds
Gallops:
150


