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静止应变分析以确定晚期慢性脏病患者心肌缺血症
Dimitrios Tsartsalis1, Yannis Dimitroglou1, Argyro Kalompatsou1
1First Department of Cardiology, 'Hippokration' Hospital, University of Athens, Medical School, Athens, Greece.
Clinical physiology and functional imaging
|February 5, 2024
概括
休息左心室变形分析可以预测心肌缺血在末期脏病患者接受压力心声. 这种技术可能有助于识别可能从冠状动脉查中受益的患者.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 医疗成像医学成像
背景情况:
- 慢性病 (CKD) 显著增加了心血管死亡风险.
- 在轻度症状的CKD患者中,冠状动脉疾病的查具有挑战性.
研究的目的:
- 评估静止变形分析在预测末期CKD患者在多布他胺应激心声图 (DSE) 期间心肌缺血的附加值.
主要方法:
- 61名末期CKD患者接受了静止心电回声和DSE.
- 测量了左心室 (LV) 喷射分数 (EF),LV全球纵向应变 (GLS) 和左心房 (LA) 应变.
- 积极的DSE结果被定义为压力诱导的LV壁运动异常.
主要成果:
- 队列显示LV缩功能保留 (平均EF49.2%),但在一半的患者中,LA菌株受损.
- 在55.7%的患者中,DSE为缺血阳性.
- LV GLS 和 LA 导管菌株与 DSE 结果有负相关性,而 LV 和 LA 尺寸与缺血有正相关性.
结论:
- 休息LV变形参数,特别是GLS,独立预测最终阶段CKD的积极DSE结果.
- LV变形分析可能有助于识别需要进一步冠状动脉查的CKD患者.
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