在患有头癌的患者中,萨科佩尼亚对吞的影响
Angela A Colback1, Daniel V Arkfeld1, Lisa M Evangelista1
1Department of Otolaryngology-Head and Neck Surgery, University of California, Davis, Sacramento, California, USA.
概括
在头癌 (HNC) 患者中,治疗前的肉类与增加的消化障碍和HNC治疗后更高的吸血风险有关. Sarcopenia 的早期识别可以指导预康复策略,以改善吞结果.
科学领域:
- 在瘤学瘤学.
- 老年学是一门学科.
- 营养科学 营养科学
背景情况:
- 骨肌肉质量下降的萨尔科佩尼亚是一种已知的因素,与头癌 (HNC) 患者的癌症结果较差有关.
- 在HNC治疗后,肉类症对吞功能的影响仍然在很大程度上未被探索.
研究的目的:
- 调查接受HNC治疗的患者治疗前治疗的肉症和吞功能障碍的发展之间的关联.
主要方法:
- 在一个学术医疗中心进行了一项回顾性队列研究.
- 治疗前的肉类的评估是使用从横截面成像获得的骨肌肉指数进行的.
- 使用患者报告的吞功能,食管依赖性和治疗前后吸入量表来评估吞功能.
主要成果:
- 在112名HNC患者中,61.6%患有治疗前的肉症.
- 萨科佩尼亚显着与患者报告的失足症风险更高相关 (OR=2.71).
- 治疗后独立预测的萨尔科佩尼亚吸收 (OR=15.18).
结论:
- 患有治疗前皮症的患者表现出更高的消化不良率,并且在HNC治疗后更容易出现吸血.
- 通过成像检测测到的 Sarcopenia 可识别出 HNC 患者有吞功能障碍的风险.
- 识别患有 sarcopenic 患者可能会优化预康复干预措施的好处.
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