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Updated: Jul 4, 2025

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小说 Bis ((2-烯胺) 与硫甲醇相关:合成,DNA相互作用,抗癌,ADMET,分子对接和DFT研究

Mohamed A Ragheb1, Fatma G Mohamed1, Hadeer M Diab2

  • 1Department of Chemistry (Biochemistry Division), Faculty of Science, Cairo University, Giza, 12613, Egypt.

Chemistry & biodiversity
|February 5, 2024
PubMed
概括

新的抗癌药物,酸烯胺与硫甲醇,显示对结肠癌细胞 (HCT116) 的强有力的活性. 化合物7e和7f抑制癌症生长,诱导亡,抑制迁移,为抗瘤药物开发提供了有希望的线索.

关键词:
双烯胺) 与硫甲醇相关.DNA / BSA 相互作用的相互作用细胞毒性 细胞毒性密度函数理论密度函数理论分子对接和ADMET特性.

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