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Updated: Jul 4, 2025

Generation of Induced Pluripotent Stem Cells from Human Melanoma Tumor-infiltrating Lymphocytes
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Generation of Induced Pluripotent Stem Cells from Human Melanoma Tumor-infiltrating Lymphocytes

Published on: November 11, 2016

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聚合体抑制复合体2抑制黑色素瘤细胞中对干扰素敏感的MHC-II表达,并与抗PD-1耐药性相关

Jamaal L James1, Brandie C Taylor1, Margaret L Axelrod2

  • 1Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Journal for immunotherapy of cancer
|February 5, 2024
PubMed
概括

向EZH2增强了瘤特异性的MHC-II表达,可能克服对免疫治疗的耐药性. 这项研究揭示了EZH2抑制是改善黑色素瘤抗PD-1/PD-L1治疗疗效的有希望的策略.

关键词:
药物治疗,组合治疗.免疫治疗是一种免疫疗法.黑色素瘤是一种黑色素瘤.瘤微环境 瘤微环境

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