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无细胞系统用于生产糖蛋白

Erik J Bidstrup1, Yong Hyun Kwon1, Keehun Kim1

  • 1Robert F. Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY, USA.

Methods in molecular biology (Clifton, N.J.)
|February 5, 2024
PubMed
概括

无细胞蛋白合成 (CFPS) 现在使得使用无细胞表达糖蛋白 (glycoCFE) 的糖蛋白生产成为可能. 这种方法克服了传统CFPS的局限性,因为它包含了治疗性蛋白质开发的必不可少的糖化机制.

关键词:
无细胞葡萄糖蛋白合成葡萄糖甘是什么? 葡萄糖甘是什么甘油的工程学是什么?葡萄糖蛋白的表达方式与脂质结合的寡糖化物.通过N链接的糖基化.有机糖转移酶 (Oligosaccharyltransferase) 是一种合成葡萄糖生物学 合成葡萄糖生物学

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