对iStent与iStent注射W相比的比较评价,在开放角玻璃眼中与发泡化相结合
Shuu Morita1, Yoshihito Sakanishi1, Ikari Riyu1
1Department of Ophthalmology, Juntendo University Urayasu Hospital, Tiba, Japan.
PloS one
|February 5, 2024
概括
无论是iStent还是iStent注射W,都有效地降低了12个月后在开角玻璃眼患者的眼内压力和药物需求. 成功率和IOP降低率相似,较低的基线IOP预测失败.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼的手术 玻璃眼的手术
- 医疗器械 医疗器械
背景情况:
- 开角玻璃眼 (OAG) 的管理通常需要药物治疗和手术干预来控制眼内压力 (IOP).
- 最少侵入性玻璃眼手术 (MIGS) 提供了传统手术的替代方案.
- iStent和iStent注射W是MIGS设备,用于与白内障手术一起使用.
研究的目的:
- 为了比较iStent和iStent注射W植入在患有开角玻璃眼患者的12个月后术后结果.
- 为了确定与这些MIGS设备的手术成功相关的因素.
主要方法:
- 一个追溯的比较病例系列分析了160名接受iStent (1支支支架) 或iStent注射W (2支支架) 植入并进行白内障手术的患者.
- 在12个月评估的结果包括眼内压 (IOP),绿眼病药物使用和生存分析.
- 手术失败是由内压升高,药物增加,内压降低不足或需要进一步手术来定义的.
主要成果:
- 在66.0%的iStent眼睛和78.4%的iStent注射眼睛在12个月后观察到治疗成功.
- 两组都显示出显著的内脏压力降低 (iStent: 8.0%;注射W: 11.9%) 和降低了药物负担,没有显著的组间差异.
- 平均内血压为iStent的13.7mmHg和iStent注射W的13.8mmHg;药物负担从2.5降至1.1 (iStent) 和2.9降至1.7 (注射W).
结论:
- 在OAG患者手术后12个月,iStent和iStent注射W都安全有效地降低了IOP和药物需求.
- 在iStent和iStent注射W组之间没有发现有效性的显著差异.
- 较低的基线内血压被确定为手术失败的预测因素.
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