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2017年至2019年印度各地角质结膜炎的流行病学:一项多中心医院研究
Ferdinamarie Sharmila1, Mini P Singh2, Jayanti Shastry3
1RVRDL, Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
Ophthalmic epidemiology
|February 5, 2024
概括
人类腺病毒 (HAdV) 是印度流行性角质结膜炎 (EKC) 的主要原因. 这项研究追踪了HAdV和其他引起结膜炎的病原体在印度的分布,持续了三年.
科学领域:
- 眼科医生 眼科 眼科
- 病毒学 病毒学
- 流行病学 流行病学
背景情况:
- 结膜炎是一种常见的眼部疾病.
- 人类腺病毒 (HAdV) 是印度流行性角质结膜炎 (EKC) 的确定的原因,之前的阳性率在1996年至2019年间从13.8%到65.2%不等.
研究的目的:
- 在印度三年时间内调查造成角质结膜炎的病原体的分布.
- 更新关于常见眼部感染的流行病学数据.
主要方法:
- 在病毒传输介质 (VTM) 中收集了709名患者的拭子.
- 使用实时PCR检测腺病毒 (HAdV),肠病毒,HSV和克拉米迪亚.
- 分析了流行病学数据和临床症状.
主要成果:
- 人类腺病毒 (HAdV) 是主要的病原体,在47.8%的阳性样本中检测到.
- 测试剂的整体阳性率为54.4%,在钱迪加 (88.4%) 和布莱尔港 (71.7%) 的比率更高.
- 耳前淋巴腺瘤和毛囊明显与膜炎风险增加有关.
结论:
- 人类腺病毒 (HAdV) 仍然是印度角质结膜炎的主要原因.
- 流行病学见解有助于预测疫情,减少不必要的抗生素使用,并改善疾病预防策略.
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