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Updated: Jun 21, 2026

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使用蛋白质纳米孔感知PEGylated形状

Remya Satheesan1,2, Devika Vikraman1,2, Parvathy Jayan3

  • 1Membrane Biology Laboratory, Transdisciplinary Biology Program, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, India.

Nano letters
|February 5, 2024
PubMed
概括

这项研究探讨了不同大小的聚乙烯糖醇 (PEG) 标记如何使用电气记录与CymA蛋白孔相互作用. 较大的PEG表现出多种形状,而较小的转位,使蛋白质组学中的特定传感应用成为可能.

关键词:
形状的变化 形状的变化目前的堵塞是当前的堵塞.这是一个纳米孔.酸是一种酸.一个单通道的单通道.

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Proteins are involved in several cellular processes and biochemical reactions. Analyzing a specific protein of interest requires it to be isolated from the other proteins in the cell. This is achieved by overexpressing the specific gene in a suitable host to produce large quantities of the target protein. A tag or label is recombined with the gene to produce a fusion protein containing the target protein and the tag. The tags on these fusion proteins can then be used for easy detection and...