诺托金森化物R1通过激活Jak1/Stat3/Mcl1通路来减轻布皮瓦卡因诱导的神经毒性

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Yu Yang1, Jiwen Wu1, Shicheng Feng1

  • 1School of Mental Health, Jining Medical University, Jining 272013, China; Shandong Collaborative Innovation Center for Diagnosis, Treatment and Behavioral Interventions of Mental Disorders, Jining Medical University, Jining, Shandong, China.

Toxicology
|February 5, 2024
PubMed
概括

诺托金化物R1 (NG-R1) 通过防止细胞死亡和细胞亡来保护布皮瓦卡因的神经毒性. 这种天然化合物激活了Jak1/Stat3/Mcl1通路,提供了潜在的治疗策略.

关键词:
细胞灭亡 (apoptosis) 是一种死亡的过程.这就是Bupivacaine.詹姆斯 (Jak1) 是一个伟大的球员.在Mcl1中.诺托基因化物R1 是一种诺托基因化物统计 统计 统计

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