相关实验视频

Updated: May 2, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

手术上更换大动脉门后患者假体不匹配:对PARTNER试验的分析

Vinod H Thourani¹, Amr E Abbas², Julien Ternacle³

¹Department of Cardiovascular Surgery, Marcus Valve Center, Piedmont Heart Institute, Atlanta, Georgia.

The Annals of thoracic surgery

|February 5, 2024

概括

手术性大动脉置换后患者与假肢不匹配 (PPM) 影响结果. 严重的PPM,特别是当测量时,与更高的死亡率有关,强调需要使用手术技术来最大限度地减少不匹配.

科学领域:

心血管外科心血管外科
人造心脏门是一种假心脏门.
临床结果研究研究

背景情况:

患者与假肢不匹配 (PPM) 是在进行大动脉置换手术 (SAVR) 后的一个潜在问题.
在SAVR后PPM的临床意义需要在大型前性试验中进一步调查.

研究的目的:

为了比较患者-假肢不匹配 (PPM) 对外科动脉置换 (SAVR) 2年后临床结果的影响.
评估预测 (PPM_P) 和测量 (PPM_M) 方法之间的PPM发生率和结果的差异.

主要方法:

从前性,随机的PARTNER 1,2和3试验中对SAVR患者的分析.
PPM被分类为中度 (指数有效孔面积 ≤0.85 cm²/m^{2) 或严重 (指数有效孔面积 ≤0.65 cm²/m^2).}
主要终点:综合所有原因死亡和心力衰竭2年后再入院.

主要成果:

测量PPM方法 (PPM_M) 与预测方法 (PPM_P) (2.1%) 相比,发现了较高的严重PPM发病率 (21.6%).
使用PPM_P,没有PPM与比中度或重度PPM更好的结果有关.
使用PPM_M,严重的PPM与没有或中度的PPM相比,与明显更糟糕的结果 (更高的死亡率和再住院) 相关.

结论:

测量PPM方法 (PPM_M) 在识别SAVR后面临不良结果风险的患者方面更为敏感.
严重的PPM,由PPM_M识别,与所有原因死亡率的增加有关.
旨在最大限度地减少PPM的手术技术对于改善长期患者结果至关重要.

更多相关视频

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Published on: June 8, 2022

相关概念视频

Mitral Valve Prolapse I: Introduction

Mitral Valve Prolapse I: Introduction

IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...

Mitral Valve Prolapse II: Assessment and Management

Mitral Valve Prolapse II: Assessment and Management

IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...