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用于长期恶性肠道阻塞的奥克特雷奥提德:两份病例报告
Sebastiano Mercadante1, Laura Tartaglia2
1Main Regional Center for Pain Relief and Supportive/Palliative Care, La Maddalena Cancer Center, Palermo, Italy; Regional Home Palliative Care Program SAMOT, Palermo, Italy.
Annals of palliative medicine
|February 5, 2024
概括
在患有恶性肠道阻塞 (MBO) 且长期缺乏便排放的患者中,奥克胺组合疗法有效地恢复了肠道通行. 这种方法被证明是有益的,即使在疾病的晚期开始.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 抚慰性护理是一种缓解性护理.
背景情况:
- 恶性肠道阻塞 (MBO) 管理通常涉及八胺,但长期缺乏便排放是一个独特的挑战.
- 对于MBO患者的干预措施存在有限的数据,这些患者在长时间内没有排便.
研究的目的:
- 评估与其他MBO药物联合使用的octreotide的疗效.
- 评估这种组合在长期缺乏便排放的情况下的有效性.
- 突出MBO中后期干预的潜力.
主要方法:
- 两名患有恶性肠道阻塞和长期缺乏便排放的患者的案例研究.
- 与支持性和息性护理措施相结合,给予奥克特雷奥提德.
- 监测肠道过渡,鼻胃管状况和口服.
主要成果:
- 两名患者在开始特胺组合治疗后两天内经历了肠道穿行恢复.
- 在这两种情况下,鼻胃管都被成功切除了.
- 在干预后,患者能够耐受口服营养.
结论:
- 即使在MBO患者中,即使在长时间没有便排放的情况下,奥克胺组合疗法也有效.
- 对于长期缺乏排便的MBO患者,应考虑采用这种治疗方法.
- 晚期干预用octreotide可以改善MBO的结果和生活质量.
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