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FSTL1通过TLR4/NF-κB通路加速细胞衰老和椎间盘退化

Xu Yan1,2, Jing-Yu Ding1,2, Ren-Jie Zhang1,2

  • 1Department of Orthopedics and Spine Surgery, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei, 230022, Anhui, China.

Inflammation
|February 5, 2024
PubMed
概括

类似于folistatin的1 (FSTL1) 通过促进衰老和炎症,驱动核脉细胞退化和椎间盘退化 (IVDD). 沉默FSTL1可以缓解IVDD的进展,这表明FSTL1是治疗腰部疼痛的治疗点.

关键词:
细胞衰老 细胞衰老在FSTL1中,FSTL1是FSTL1.IVDDDD IVDD 是一个很好的方法.在 TLR4/NF-κBB 中.

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