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Updated: Jul 4, 2025

Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization
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在使用GWAS总结统计数据的家庭样本中进行基因关联测试

Peng Wang1, Xiao Xu2, Ming Li2

  • 1Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Hubei, People's Republic of China.

Genetic epidemiology
|February 6, 2024
PubMed
概括

新的方法允许基于基因的关联测试使用全基因组关联研究 (GWAS) 从家庭样本的总结统计数据. 这种方法适应了现有的工具,用于与人无关的个体,使得更广泛的遗传研究能够在没有个人级别数据的情况下进行.

关键词:
关于GWAS总结数据的总结这是一个LD矩阵.家庭样本 家庭样本基因相关性测试基因相关性测试线性混合模型线性混合模型

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