黄素和超过的素或乳清蛋白之间的相互作用,以及它们的复合物的特征
Hao Wu1, Juanjuan Qin1, Wei Ji1
1College of Science, Gansu Agricultural University, Lanzhou, China.
Journal of food science
|February 6, 2024
概括
状素 (MC) 和乳清蛋白 (WP) 有效地与黄素 (Cur) 结合,增强其特性. 这些蛋白质-黄素复合物显示出更好的溶解性和抗氧化活性,使它们成为有价值的活性食品成分.
科学领域:
- 食品科学 食品科学 食品科学
- 生物化学 生物化学
- 材料科学 材料科学 材料科学
背景情况:
- 黄素 (Cur) 是一种具有有限生物可用性的生物活性化合物.
- 像状素 (MC) 和乳清蛋白 (WP) 这样的蛋白质可以作为生物活性化合物的载体.
- 超过保留剂是这些蛋白质的来源.
研究的目的:
- 调查MC或WP和Cur.之间的相互作用.
- 评估Cur-MC和Cur-WP复合物的物理化学和功能性质.
- 探索这些复合物作为活性食品成分的潜力.
主要方法:
- 有约束力的研究,以确定亲和力和热力学参数.
- 对复杂的尺寸,多分散性和形态学的分析.
- 评估水溶性,激素清除活性和体外胃肠道释放.
主要成果:
- 对于Cur,MC表现出比WP更高的结合亲和力.
- 库尔和蛋白质之间的相互作用主要是疏水的.
- 库尔-蛋白质复合体表现出增强的水溶性,抗氧化活性和可控释放的库尔.
- 喷雾干燥的复合物没有改变它们的形态.
结论:
- MC和WP是适合的基于蛋白质的载体,用于Cur的传递.
- 由此产生的Cur-蛋白质复合物具有有益的功能性质,可用于食品应用.
- 喷雾干燥的MC-Cur和WP-Cur复合物可以作为有效的活性食品成分.
更多相关视频
05:08Solubility of Hydrophobic Compounds in Aqueous Solution Using Combinations of Self-assembling Peptide and Amino Acid
Published on: September 20, 2017
16.8K
10:20In vitro Digestion of Emulsions in a Single Droplet via Multi Subphase Exchange of Simulated Gastrointestinal Fluids
Published on: November 18, 2022
2.5K
相关概念视频
Factors Affecting Protein-Drug Binding: Drug Interactions
140
Drug interactions are a critical aspect of pharmacology and can occur when two or more drugs compete for the same binding site. This competition can result in one drug displacing another, altering the effect of the displaced drug. Drug interactions are complex processes that rely heavily on how much of the displacer drug is present and how strongly it can bind to the same sites as the displaced drug.
Displacement interactions can have varying outcomes, ranging from toxicity to virtually...
Displacement interactions can have varying outcomes, ranging from toxicity to virtually...
140
Detergent Purification of Membrane Proteins
5.2K
Detergents are used to purify the integral proteins of the membrane. The hydrophobic portion of the detergent can replace membrane phospholipids while solubilizing the membrane proteins. When detergent monomers reach a specific concentration in a solution called critical micelle concentration (CMC), they form micelles. Above CMC, the concentration of the detergent monomers remains in equilibrium with the micelle. The number of detergent monomers present in the CMC varies for each detergent, and...
5.2K
