患有慢性鼻炎的成年人中的性别差异:一个范围审查
John Behnke1, Caroline Dundervill2, Zayd Al-Asadi2
1Department of Otolaryngology, West Virginia University, Morgantown, Virginia University, USA.
概括
患有慢性鼻炎 (CRS) 的女性报告生活质量比男性差,尽管治疗结果相似. 需要对CRS病理生理学的进一步研究来解释这些基于性别的差异.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 鼻科 鼻科是指鼻科的专家.
- 流行病学 流行病学
背景情况:
- 慢性鼻炎 (CRS) 影响全球数百万人,新出现的证据表明其呈现和影响存在基于性别的变化.
- 了解这些性别差异对于个性化患者护理和有针对性的研究至关重要.
研究的目的:
- 对有关慢性鼻炎性别差异的现有文献进行范围审查.
- 识别性别之间关于CRS呈现,病理生理学和治疗结果的知识差距.
主要方法:
- 在PubMed,Cochrane图书馆和Embase数据库的系统文献搜索.
- 遵守系统审查和元分析的优先报告项目 扩展范围审查 (PRISMA-ScR) 准则.
- 包括23项评估CRS表现,病理生理学或治疗结果的性别差异的研究.
主要成果:
- 与男性相比,患有CRS的女性报告了与男性相比显著更差的基线生活质量 (QoL).
- 十一项研究研究了呈现差异,五项研究了病理生理学,十项研究分析了治疗结果.
- 治疗结果,无论是外科还是医疗,尽管基线QoL不同,但两种性别的治疗结果总体上相似.
结论:
- 慢性鼻炎的主观负担在女性中比男性更大.
- 在性别之间的CRS经验中发现的差异需要进一步调查.
- 未来的研究应该优先探索CRS的病理生理学,以阐明这些性别特异性变异背后的原因.
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