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Updated: Jul 4, 2025

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA
11:35

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA

Published on: August 21, 2016

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在SLC15A4中的一个非编码变体调节了增强器活动和与狼易感性相关的溶酶体脱酸

Manish Kumar Singh1, Guru Prashad Maiti1, HariKrishna Reddy-Rallabandi1

  • 1Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City OK, USA.

Frontiers in lupus
|February 6, 2024
PubMed
概括

一种特定的基因变异rs35907548,靠近SLC15A4基因可能会增加对系统性红斑狼 (SLE) 的敏感性. 这种风险等位基因改变了基因调节和细胞功能,可能有助于SLE发展.

关键词:
克里斯普尔是什么意思?克里斯普尔是什么意思?这就是ChIP-qPCR.路西法拉斯就是路西法拉斯.狼是一种狼.Lysosomal 酸性化发生的原因在SLC15A4A4中使用.

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