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Updated: Jul 4, 2025

Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy
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在C-Myc/H19/miR-29b轴下调神经/质 (NG) 2表达在多形质母细胞瘤

Anne S Boewe1, Selina Wrublewsky1, Jessica Hoppstädter2

  • 1Institute for Clinical and Experimental Surgery, Saarland University, 66421 Homburg, Germany.

Molecular therapy. Nucleic acids
|February 6, 2024
PubMed
概括

微RNA-29b (miR-29b) 通过降低神经/质抗原2 (NG2) 表达的调节来抑制多形质母细胞瘤 (GBM) 的生长. 这种由c-Myc和H19调节的miR-29b/NG2轴为GBM提供了潜在的治疗点.

关键词:
H19 H19 是一种H19病毒.MT:非编码RNAs的使用.NG2 NG2 NG2 NG2 NG2 NG2 NG2 NG2 NG2 NG2 NG2 NG2 NG2 NG2 NG2这是PDGFRα.c-Myccc 的意思是我的质母细胞瘤多形这就是miR-29b.移民 移民 迁移 迁移它们的扩散和扩散.

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