在使用毒品的人群中使用达尔巴万辛可能会增加吸毒的坚持,而不会增加成本
Tiffany A Russo1, Hannah R Ritchie2, Jennifer J Schimmel3,4
1Department of Pharmacy, Middlesex Health, Middletown, CT, USA.
概括
达尔巴万辛 (DAL) 可能会改善感染药物使用者 (PWUD) 完成治疗. 虽然DAL的使用显示出更高完成率的趋势,但与标准治疗相比,金融贡献利没有显著差异.
科学领域:
- 传染性疾病 传染性疾病
- 药物经济学 药物经济学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 达尔巴万辛 (DAL) 为接受门诊感染治疗的吸毒者 (PWUD) 提供了一种潜在的解决方案,解决了IV接入滥用问题的问题.
- 在采用DAL时的犹源于高成本和保险退款挑战.
- 本研究评估了与DAL使用相关的财务影响和治疗完成率.
研究的目的:
- 确定达尔巴万辛 (DAL) 对使用毒品的人 (PWUD) 的财务影响.
- 评估DAL对医疗保健利用率和治疗完成率的影响.
- 为了比较DAL与传统治疗方案的成本效益.
主要方法:
- 追溯队列研究,将接受DAL治疗的患者与对照组进行比较.
- 分析实际测量成本和医疗保健利用数据.
- 对黄金杆菌菌菌的治疗完成率的评估.
主要成果:
- 在2020年6月至2022年1月期间,29个PWUD获得了DAL.
- 在接受DAL的患者中,66%的患者完成了治疗,对照组的55%患者完成了治疗.
- 对DAL的贡献率为7180美元,而对照组为6655美元,这是非统计学上显著的差异 (P=0.47).
结论:
- 在吸毒者 (PWUD) 中使用达尔巴万辛 (DAL) 可能会提高感染治疗完成率.
- 在DAL和标准治疗之间,没有发现贡献率的统计学上显著差异.
- 在特定的患者群体中,DAL为改善患者的坚持提供了潜在的选择.
相关概念视频
Pulmonary Tuberculosis V
180
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
180
Drug Delivery: Parenteral Route
532
The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
532
Drug Dosage Regimen: Overview
3.5K
A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
3.5K
Drug Therapy
44
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
44
Dosage Regimen: Fixed Dose
1.9K
Fixed-dose regimens are a common approach to administer drugs to achieve and maintain desired levels of the drug in the body. In this dosing strategy, a specific amount of medication is given at regular intervals, often multiple times a day, to ensure a consistent drug concentration in the bloodstream.
Fixed-dose regimens can be used for various routes of administration, including intravenous (IV) injections and oral medications. For IV administration, a predetermined amount of the drug is...
Fixed-dose regimens can be used for various routes of administration, including intravenous (IV) injections and oral medications. For IV administration, a predetermined amount of the drug is...
1.9K
Combined Effects of Drugs: Synergism
3.9K
Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
Such synergistic combinations...
3.9K


