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Updated: Jul 4, 2025

Assessing Mitochondrial Function in Sciatic Nerve by High-Resolution Respirometry
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Assessing Mitochondrial Function in Sciatic Nerve by High-Resolution Respirometry

Published on: May 5, 2022

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缺陷的tRNA转录后修饰失调了线粒体质量控制和亡

Yunfan He1,2,3, Gao Zhu1,2,3,4, Xincheng Li2

  • 1Center for Mitochondrial Biomedicine, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, Zhejiang, China.

iScience
|February 6, 2024
PubMed
概括

线粒体DNA (mtDNA) 突变通过破坏氧化酸化和自破坏细胞完整性. 这项研究揭示了特定的tRNA突变如何触发这些缺陷,促进细胞死亡.

关键词:
细胞生物学 细胞生物学分子生理学分子生理学生物分子的特性

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