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Updated: Jul 13, 2026

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
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基于调节器操纵和媒介优化的结合策略使林科米的生物合成过度生产成为可能

Xinlu Cai1, Wanlian Xu1, Yang Zheng1

  • 1School of Life Sciences, Institute of Physical Science and Information Technology, Anhui University, Hefei, 230601, China.

Synthetic and systems biotechnology
|February 6, 2024
PubMed
概括

研究人员通过基因改造*Streptomyces lincolnensis**来增强林氏素A (Lin-A) 抗生素的产生. 删除两个关键抑制剂SLCG_4846和SLCG_2919,并优化发酵条件显著提高了Lin-A产量.

关键词:
发酵优化优化发酵的优化基因工程是一种基因工程.林科米辛 (Lincomycin) 是一种药物.这种病名为Streptomyces.转录因子是一种转录因子.

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