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Updated: Jul 4, 2025

Deciphering High-Resolution 3D Chromatin Organization via Capture Hi-C
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Deciphering High-Resolution 3D Chromatin Organization via Capture Hi-C

Published on: October 14, 2022

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补充Hi-C信息用于使用ChromStruct进行3D染色体重建

Claudia Caudai1, Emanuele Salerno1

  • 1Institute of Information Science and Technologies, National Research Council of Italy, Pisa, Italy.

Frontiers in bioinformatics
|February 6, 2024
PubMed
概括

本研究评估了一种用于重建3D染色质结构的多尺度方法,使用Hi-C数据与ChIP-seq,RNA-seq和ChIA-PET相结合. 整合多样化的数据可以改善染色体建模,特别是当Hi-C数据不完整时.

关键词:
三维染色体配置的3D染色体配置结合DNA的因素 结合DNA的因素Hi-C 联系人数据 联系人数据基因表达数据 基因表达数据基斯顿基因基因基因基因基因基因基因基因基因基因基因基因基因修改的珠子链模型模型.多尺度重建算法 多尺度重建算法

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