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Updated: Jul 4, 2025

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
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Published on: September 18, 2016

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一个Pd催化无效化策略对线性融合的功能化N-异循环

Larry Hoteite1, Benjamin D W Allen1, Ms Ergaiya A Elhajj1

  • 1The Department of Chemistry, The University of Sheffield, Sheffield, S3 7HF, U.K.

Chemistry (Weinheim an der Bergstrasse, Germany)
|February 6, 2024
PubMed
概括

我们开发了一种催化方法,从简单的前体中制造化多环形皮佩里丁. 这种高效的策略允许选择性功能化和对合成有价值的含分子中的立体化学进行控制.

关键词:
类基化化.催化剂是一种催化剂.在 diastereoselective 中进行选择.这是enantioselective选择性的.皮佩里迪因 (Piperidine) 是一种药物.

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Cycloadditions are one of the most valuable and effective synthesis routes to form cyclic compounds. These are concerted pericyclic reactions between two unsaturated compounds resulting in a cyclic product with two new σ bonds formed at the expense of π bonds. The [4 + 2] cycloaddition, known as the Diels–Alder reaction, is the most common. The other example is a [2 + 2] cycloaddition.
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