超越杆菌病:解开并发感染和改变免疫力
Dilhan J Perera1,2, Cal Koger-Pease1,2, Kayla Paulini3
1Division of Experimental Medicine, McGill University, Montreal, Canada.
Clinical microbiology reviews
|February 6, 2024
概括
甲状腺,一种寄生性疾病,经常与其他病原体共感染,改变疾病严重程度和免疫反应. 了解这些复杂的相互作用对于开发有效的治疗方法和疫苗来对抗杆菌病至关重要.
科学领域:
- 热带医学是一种热带医学.
- 寄生虫学的寄生虫学
- 免疫学 免疫学 免疫学
背景情况:
- 石病是一种主要的被忽视的热带疾病,由*Schistosoma*属的虫引起.
- 传染发生在热带和亚热带地区的受污染的淡水中.
- 与 * Schistosoma * 的同时感染很常见,但研究不足.
研究的目的:
- 审查有关 * Schistosoma * 共感染影响的文献.
- 检查共感染如何改变疾病严重程度和免疫格局.
- 突出了解共感染对于未来干预的重要性.
主要方法:
- 文献综述最近关于 * Schistosoma * 共感染的研究.
- 对与其他虫,原生动物,细菌 (*Mycobacterium*, *Salmonella*) 和病毒的同时感染的分析.
- 专注于疾病严重程度和免疫反应的变化.
主要成果:
- 与 * Schistosoma * 的同时感染会改变各种病原体类型的疾病严重程度.
- 免疫系统的格局受到 * Schistosoma * 联合感染的显著改变.
- 具体的例子包括与土壤传播的虫,肠道原生动物和病毒病原体的共同感染.
结论:
- 杆菌共感染对宿主免疫力和疾病结果有重大影响.
- 对这些相互作用的进一步研究对于有效控制杆菌病至关重要.
- 了解共同感染对于开发有针对性的治疗策略和新型疫苗候选人至关重要.
相关概念视频
Immunodeficiency Diseases
940
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
There are three main causes of immunodeficiency...
940
Factors Affecting the Risk of Infection
11.8K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.8K
Pulmonary Tuberculosis I
243
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
243
Chronic Bowel Disorders: Introduction
450
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
450
Sexually Transmitted Infections
315
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
315
Symbiosis
28.0K
Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...
28.0K


