光学连贯断层扫描和剪切波弹性学发现在格雷夫斯眼科医院
Eren Gürkan1, Ayşe İdil Çakmak2, Gülen Burakgazi3
1Department of Endocrinology and Metabolism, Medical Faculty of Tayfur Ata Sökmen, University of Hatay Mustafa Kemal, Alahan Mah, 31001, Hatay, Turkey. erengurkan71@gmail.com.
International ophthalmology
|February 6, 2024
概括
剪切波弹性图 (SWE) 和光学连贯性断层扫描 (OCT) 在Graves眼病 (GO) 患者中显示出显著的变化. 这些成像方法可以与临床评估一起帮助监测疾病严重程度.
科学领域:
- 眼科医生 眼科 眼科
- 医疗成像医学成像
- 内分泌学 在内分泌学.
背景情况:
- 格雷夫斯眼病 (GO) 是一种影响眼睛的自身免疫性疾病,其特征是炎症和组织变化.
- 评估GO活动和严重程度对于有效管理至关重要.
- 图像化模式可以提供疾病进展的客观指标.
研究的目的:
- 评估光学连贯断层扫描 (OCT) 和剪切波弹性扫描 (SWE) 在评估格雷夫斯眼科医症 (GO) 严重性的实用性.
- 为了比较轻度GO患者和健康对照患者之间的成像发现.
主要方法:
- 在32名轻度GO患者和健康对照组中比较了OCT和SWE发现.
- 使用第三代测定方法测量了TSH受体抗体 (TRAb) 血清水平.
- 分析了视神经外直径 (ONSD),视神经 (ON) 弹性和视网膜神经纤维层 (RNFL) 厚度.
主要成果:
- GO患者在两只眼睛中表现出增加的ONSD和ON弹性,以及右眼的软组织弹性增加.
- 在GO组中观察到左RNFL和周囊RNFL显著稀释.
- 在左眼OCT和SWE发现之间发现了相关性,特别是在TRAb阳性患者中.
结论:
- SWE和OCT揭示了GO患者眼睛的显著结构和弹性变化.
- 这些成像技术与疾病活性相关,可以补充临床评分和TRAb水平.
- SWE和OCT显示出作为监测GO进步的工具的前景.
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