视野缺陷在阿尔比尼斯症相比,与异常发病的婴儿肌
Viral Sheth1,2, Rebecca J McLean2, Zhanhan Tu2
1Health Sciences School, University of Sheffield, Sheffield, Yorkshire, United Kingdom.
Investigative ophthalmology & visual science
|February 6, 2024
概括
患有白化症 (PwA) 和特异性婴儿眼 (PwIIN) 的人具有显著的视野 (VF) 缺陷. 白化会导致比尼斯塔格姆更严重的VF损失,这表明PWA中的VF缺陷不仅仅是由于尼斯塔格姆.
科学领域:
- 眼科医生 眼科 眼科
- 神经科学是一个神经科学.
- 遗传学 是一个遗传学.
背景情况:
- 白化和异常发育的婴儿鼻是影响视力的疾病.
- 在这些条件下,视野缺陷很常见,但其特定特征和原因尚未完全理解.
研究的目的:
- 使用静态周边测量,系统地比较白化 (PwA) 和异常婴儿眼 (PwIIN) 患者的视野 (VF) 缺陷.
- 为了比较最佳校正的视敏度 (BCVA) 和光学连贯性断层扫描 (OCT) 测量PWA中的视网膜层.
主要方法:
- 静态周边测量 (汉弗里场分析仪,SITA FAST 24-2) 对62个PWA和36个PWIIN进行了测试.
- 每只眼睛的平均检测值,象限和中心尺度都被计算出来.
- 视网膜层在黄斑区域手动细分,用于OCT分析.
主要成果:
- 普华永道和普华永道都显示平均检测值明显低于规范值.
- 普华永道的门值明显低于普华永道,表明了更严重的虚拟货币赤字.
- PwA表现出较大的左眼缺陷和特定的上鼻VF损伤,与形变化和BCVA相关.
结论:
- 普华永道和普华永道都存在显著的边缘和中央虚拟货币赤字.
- 普华永道的VF缺陷可能不仅仅是由于鼻,因为它们的严重程度比普华永道更大.
- PwA显示复杂的VF不对称性 (水平,垂直,整眼),需要进一步调查.
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