在轻度认知障碍患者的大脑训练的十字字
Milap A Nowrangi1, Tracy D Vannorsdall1, Paul B Rosenberg1
1Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore.
NEJM evidence
|February 6, 2024
概括
脑部训练,包括指导精神炼,可能有助于预防健康成年人的痴呆症. 有证据表明,认知训练对处理速度和日常功能有好处,可能降低痴呆症风险.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 公共卫生 公共卫生
背景情况:
- 痴呆症的患病率和公共卫生影响需要有效的预防策略.
- 大脑训练,定义为针对认知领域的指导精神练习,是一种有前途的方法.
- 现有证据包括幼儿教育的保护作用和ACTIVE试验结果.
研究的目的:
- 探索大脑训练作为痴呆症预防策略的潜力.
- 审查支持痴呆症预防认知训练的证据.
主要方法:
- 对大脑训练现有证据的审查.
- 分析了ACTIVE (独立和有生命力的老年人高级认知训练) 试验结果.
主要成果:
- 大脑训练可以预防认知完好成人的痴呆症.
- 该ACTIVE试验在处理速度方面展示了长期的认知益处.
- 认知训练可以降低痴呆症的发生率,改善日常功能.
结论:
- 大脑训练是预防痴呆症的一个有希望的途径.
- 认知干预可以产生持久的认知效益和功能改善.
更多相关视频
07:01Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment
Published on: September 20, 2020
4.7K
07:35Author Spotlight: Rehabilitation of Stroke Patients With a Digital Occupational Training System
Published on: December 29, 2023
1.2K
相关概念视频
Cognitive Development During Adulthood
111
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
111
Alzheimer's Disease: Treatment
193
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
193
Alzheimer's Disease: Overview
487
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
487
Dementia
115
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
115
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
126
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
126
