预测角膜内环段对角质的视觉结果的因素
Apisit Khanthik1, Ngamjit Kasetsuwan1,2, Sasi Yaisawang1
1Faculty of Medicine, Department of Ophthalmology, Chulalongkorn University, Bangkok, Thailand.
PloS one
|February 6, 2024
概括
在角质患者的角质内环段 (ICRS) 植入后视力敏度变化的预测模型被开发出来. 手术前的诸如视力敏度和角质测量等因素有助于预测结果,有助于手术规划和患者咨询.
科学领域:
- 眼科医生 眼科 眼科
- 角膜外科手术 角膜外科手术
- 视觉科学科学 视觉科学
背景情况:
- 角膜是一种渐进的角膜脱落,导致不规则的纹和视力丧失.
- 角膜内环段 (ICRS) 用于调节角膜并改善角膜患者的视力敏度.
- 在ICRS植入后预测视力敏度结果对于管理患者期望和优化手术成功至关重要.
研究的目的:
- 为了确定预手术因素,预测ICRS植入后视力敏度的变化.
- 开发和验证ICRS手术中的角患者视力敏度结果的预测模型.
主要方法:
- 从230名接受ICRS植入的患者中对287个形眼睛进行了回顾性审查.
- 数据包括流行病学和临床手术前变量,包括Scheimpflug断层扫描.
- 多重线性回归分析用于培训组开发预测模型,并在验证组进行测试.
主要成果:
- 手术前纠正距离视力敏度 (CDVAp) 是CDVA变化的强有力的预测指标 (Beta = -0.746).
- 对于未经纠正和纠正的远距离视敏度 (ΔUDVA和 ΔCDVA) 变化的模型包括手术前视敏度,角质量测量和表面方差指数.
- 预测模型在验证组中分别为 ΔUDVA 和 ΔCDVA 实现了 47.83% 和 63.4% 的精度,在 0.20 logMAR 范围内.
结论:
- 手术前的因素可以预测ICRS植入后视力敏度的变化.
- 开发的预测模型可以作为临床医生的辅助工具.
- 这些工具可以帮助患者选择和手术前咨询,以提高形管理中的外科手术结果.
相关概念视频
01:24Vision
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
01:20Anatomy of the Eyeball
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle layer, the vascular tunic,...
01:22Photoreceptors and Visual Pathways
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...