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Updated: Jul 4, 2025

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
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在阿司匹多精和伊波加类生物合成中,碳酸类 [4+2] 循环酶的演变和多样化

Matthew D DeMars1, Sarah E O'Connor1

  • 1Department of Natural Product Biosynthesis, Max Planck Institute for Chemical Ecology, Jena 07745, Germany.

Proceedings of the National Academy of Sciences of the United States of America
|February 6, 2024
PubMed
概括

植物酶的进化揭示了复杂的单烯醇化物 (MIA) 如何形成,如阿司匹多精和伊波加化物. 这项研究追溯了MIA生物合成中的关键循环酶的祖先起源和多样化.

关键词:
祖先的序列重建的重建.这是一个循环加法循环.单二醇醇类化合物 单二醇类化合物自然产品的生物合成.

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