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Updated: Jul 4, 2025

Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss
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Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss

Published on: July 19, 2024

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肝脏微生物组与表观基因组之间的交叉交谈在患有与代谢功能障碍相关的脂肪性肝病的患者中

Carlos Jose Pirola1, Adrian Salatino2, Tomas Fernández Gianotti3

  • 1Systems Biology of Complex Diseases, Translational Health Research Center (CENITRES), Maimónides University, Buenos Aires, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina; Faculty of Health Science, Maimónides University, Buenos Aires, Argentina.

EBioMedicine
|February 6, 2024
PubMed
概括

肝脏表观基因组,包括酸转移酶 (HAT) 活性和DNA基甲基化,在代谢功能障碍相关的脂肪性肝病 (MASLD) 中受到肝脏微生物组的影响. 这些表观遗传变化与疾病的严重程度和特定细菌的丰度相关.

关键词:
5 - - 氧甲基细胞氨酸.表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.帽子 帽子 帽子在HDAC的基础上,HDAC是马斯尔德 马斯尔德是什么意思微生物群中的微生物群这是NAFLD.

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