在17,491名患有高血症的患者中检测原发性甲状腺功能障碍症
Paul M Bunch1, Joseph Rigdon2, Leon Lenchik1
1Department of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina.
只有35%的高血症患者进行了初级甲状腺功能障碍症 (PHPT) 测试. 在患有脏病或骨质疏松症等并发症的患者中,测试更为常见,但在年轻的患者或患有抑郁症的患者中,测试的可能性较小.
科学领域:
- 内分泌学 在内分泌学.
- 内部医学 内部医学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 初级甲状腺功能障碍症 (PHPT) 经常被低诊断,尽管它与显著的不良健康影响有关.
- 从历史上看,副甲状腺激素 (PTH) 测试并没有在所有高热血症患者中得到一致的应用,这一差距的原因尚不清楚.
研究的目的:
- 为了确定在一个大型的学术卫生系统内的高血症个体中PTH测试的速度.
- 为了确定与PTH测试相关的或与PTH测试相关的患者特征.
- 为旨在改善PHPT诊断率的战略提供信息.
主要方法:
- 对于在2018年至2022年期间至少有一次血清水平升高的成年患者的回顾性分析.
- 患者被分为"选" (PTH测试) 或"未选"组.
- 查和未查群体之间的人口和临床特征的比较.
主要成果:
- 在17491名高血症患者中,只有34.9% (6096) 接受了PTH测试.
- 显著增加测试几率的因素包括多次升高的结果,慢性病,非常高的水平 (>12.0 mg/dL) 和骨质疏松症.
- 与较低测试几率相关的因素包括年龄较小 (<35岁),年龄较大 (≥85岁) 和抑郁症.
结论:
- 该研究显示,高血症患者中PTH测试率较低 (35%).
- 虽然伴随性疾病通常会增加测试的可能性,但患有抑郁症的患者显示,接受PHPT测试的可能性下降了16%.
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