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卡塔尔恶性淋巴瘤的流行病学和临床模式 2013-2017:基于人口的队列研究

Ahmad M Adel¹, Aimilia Exarchakou², Nurhan Elshafey³

¹Department of Pharmacy, National Center for Cancer Care and Research, Hamad Medical Corporation (HMC), Doha, Qatar.

|February 6, 2024

概括

在卡塔尔,霍奇金淋巴瘤 (HL) 显示出比非霍奇金淋巴瘤 (NHL) 更好的生存率. 这项研究比较了2013年至2017年期间诊断的成年淋巴瘤患者的整体存活率.

科学领域:

血液瘤学血液瘤学
恶性瘤的流行病学

背景情况:

淋巴瘤,包括非霍奇金淋巴瘤 (NHL) 和霍奇金淋巴瘤 (HL),构成重要的血液恶性瘤.
治疗的进步改善了结果,但复杂性需要不同的管理和观察策略.

研究的目的:

为了比较2013-2017年卡塔尔成年患者HL和NHL的整体存活率 (OS).
分析HL和NHL的流行组织学类型,临床和流行病学特征.
评估临床特征,治疗,反应和无病生存率.

主要方法:

在卡塔尔2013-2017年间诊断的414例淋巴瘤病例的回顾性,描述性研究.
纳入标准:患者≥18岁,接受化疗,已知结果.
使用卡普兰-梅尔曲线进行生存分析;使用STATA 13.0.0分析数据.

主要成果:

诊断时的中位数年龄为49岁;男性在HL (74%) 和NHL (70%) 中都占主导地位.
总体而言,1年,3年和5年的生存率分别为99%,82%和64%.
与非霍奇金淋巴瘤 (NHL) 相比,霍奇金淋巴瘤 (HL) 的3年 (94%对82%) 和5年 (67%对60%) 的生存率显著更高 (p < 0.001).

结论:

扩散性大B细胞淋巴瘤是卡塔尔最常见的NHL亚型.
与非霍奇金淋巴瘤 (NHL) (60%) 相比,霍奇金淋巴瘤 (HL) 一般表现出更高的生存率 (67%).
在HL的潜在小生存率通缩可能与卡塔尔的移民模式有关.

关键词:

流行病学流行病学霍奇金淋巴瘤是一种霍奇金淋巴瘤.淋巴瘤是一种淋巴瘤.非霍奇金淋巴瘤非霍奇金淋巴瘤卡塔尔卡塔尔卡塔尔卡塔尔

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