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血蛋白质组的全转录组关联研究揭示了复杂特征背后的 cis 和 trans 调节机制

Henry Wittich1, Kristin Ardlie2, Kent D Taylor3

  • 1Program in Bioinformatics, Loyola University Chicago, Chicago, IL 60660, USA.

American journal of human genetics
|February 6, 2024
PubMed
概括

这项研究将基因表达与血蛋白水平联系起来,识别出 cis 和 trans 作用的基因. 基因调节的基因表达更好地预测蛋白质水平,有助于复杂的特征分析.

关键词:
在TWAS中,TWAS就是TWAS.自身免疫性疾病 自身免疫性疾病在 cis-eQTL 中.基因表达的基因表达方式遗传预测 遗传预测遗传性 遗传性 遗传性血蛋白质组中的血蛋白质组通过 trans-eQTL.转录因子是一种转录因子.

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