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Updated: Jul 4, 2025

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MT-TN突变导致渐进的线粒体脑病变,并促进线粒体的发生

Haolin Duan1, Cunhui Pan1, Tenghui Wu1

  • 1Department of Pediatrics, Clinical Research Center of Children Neurodevelopmental Disabilities of Hunan Province, Xiangya Hospital, Central South University, Changsha 410008, China.

Biochimica et biophysica acta. Molecular basis of disease
|February 6, 2024
PubMed
概括

在MT-TN基因的突变导致线粒体脑病变通过损害能量生产. 这项研究确定了两个新的MT-TN突变,详细介绍了它们对线粒体功能的影响,并扩大了这种神经系统疾病的已知的临床谱.

关键词:
是一种病.在MT-TN中使用.线粒体脑病变 - 线粒体脑病变线粒细胞衰变 (mitophagy) 是一种

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