针对喘缓解作为改善疾病控制的下一个治疗步骤
William W Busse1, Geoffrey Chupp2, Thomas Corbridge3
1Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin, Madison, Wis.
The journal of allergy and clinical immunology. In practice
|February 6, 2024
概括
临床缓解是喘管理的一个可实现的目标,重点是控制症状并减少未来的风险. 实现这一目标需要共享决策和对患者的统一理解.
科学领域:
- 肺病学和呼吸系统医学
- 临床免疫学临床免疫学
- 翻译医学是一种翻译医学.
背景情况:
- 喘管理传统上侧重于症状控制和风险分层.
- 精准医学的进步,包括生物药物,已经扩大了治疗的可能性.
- 临床缓解,在喘中以前不常见,正在成为潜在的治疗目标.
研究的目的:
- 讨论治疗期间的临床缓解作为喘管理中的理想结果.
- 将其与其他慢性疾病的缓解目标进行比较.
- 强调共享决策和统一的患者旅程理解的重要性.
主要方法:
- 关于喘临床缓解的文献综述和专家讨论.
- 对喘缓解定义的现有框架的分析.
- 从其他慢性疾病管理中探索缓解概念.
主要成果:
- 2020年专家框架启动了喘临床缓解的定义.
- 关于喘缓解的标准化临床参数和值,目前仍在进行辩论.
- 共同决策对于定义和实现缓解至关重要.
结论:
- 在治疗过程中临床缓解代表了喘管理的理想结果.
- 定义和实现缓解可以显著降低疾病负担.
- 患者和专业人士之间的协作理解是改善喘结果的关键.
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