皮肤病学结果领域范围审查协议
Umer Nadir1, Areeba Ahmed1, Michael D Yi1
1Department of Dermatology, Feinberg School of Medicine, Chicago, Illinois, USA.
BMJ open
|February 6, 2024
概括
本范围审查映射和分类皮肤病核心结果集 (COS) 项目的结果. 它旨在识别和组织皮肤病学临床试验和实践中使用的概念和工具.
科学领域:
- 皮肤病学 皮肤病学
- 临床试验 临床试验
- 结果测量 结果测量
背景情况:
- 核心结果集 (COSs) 在临床研究中标准化结果测量.
- 越来越多的COS存在,可能导致领域和工具的概念重叠.
- 在皮肤病学中标准化结果测量对于可比的临床试验结果至关重要.
研究的目的:
- 进行皮肤疾病相关的COS倡议的范围审查.
- 识别,绘制和分类在这些COS中使用的所有结果概念和工具.
- 解决潜在的重叠问题,促进皮肤病结果测量的协调.
主要方法:
- 来自PubMed,Embase和Cochrane图书馆 (2010-2024) 的文献范围审查.
- 包括从有效性试验 (COMET) 数据库和C3网站的核心成果措施数据的数据.
- 通过与COS,皮肤病学和患者组织的利益相关方参与,进行补充数据收集.
主要成果:
- 从皮肤病COS项目中确定一个全面的结果概念和工具列表.
- 将确定的结果分类为概念上相似的类别.
- 绘制领域和工具的地图,以了解重叠和识别差距.
结论:
- 该审查将提供皮肤病研究结果测量的结构化概述.
- 这些发现将有助于协调未来皮肤病临床试验的结果选择.
- 这项工作支持皮肤病学核心结果集的开发和完善.
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