综合系统性免疫炎症指数 (SII) 和老年营养风险指数 (GNRI) 预测骨骨折的老年患者的生存率:一项回顾性研究
Ling Zhou1,2, Chao Huang3, Xianjie Zhu2
1Graduate School of Dalian Medical University, Dalian, China.
Journal of orthopaedic surgery and research
|February 6, 2024
概括
综合的系统免疫炎症指数 (SII) 和老年营养风险指数 (GNRI) 评分预测了老年关节骨折患者的死亡率. 高SII-GNRI得分表明手术后1年死亡风险增加.
科学领域:
- 老年医学 老年医学
- 整形外科手术 整形外科手术
- 炎症学 炎症学
背景情况:
- 系统性免疫炎症指数 (SII) 和老年营养风险指数 (GNRI) 是经过验证的预后标志物.
- 它们在预测关节骨折患者预后的综合实用性仍未得到充分研究.
研究的目的:
- 调查SII-GNRI综合得分是否是老年关节骨折患者结果的独立预测指标.
- 评估SII-GNRI得分对部骨折手术后1年死亡率的预后价值.
主要方法:
- 对597名患有关节骨折的老年患者进行了回顾性分析 (大腿部和关节间骨折).
- 计算SII和GNRI得分,ROC曲线分析以确定最佳的切线.
- 多变量考克斯回归分析,以评估SII-GNRI得分与1年死亡率的关联.
主要成果:
- 在1年内死亡的患者中观察到显著更高的SII-GNRI得分.
- 高SII-GNRI得分独立预测了老年关节骨折患者1年的全因死亡率.
- 高SII-GNRI得分与术后并发症的发生率更高相关.
结论:
- 在SII-GNRI得分是预测1年生存率的有价值的工具在接受手术的老年关节骨折患者.
- 这种综合指数提供了超越传统风险因素的预测见解.
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