与商业实验室分析仪相比,猫血的分析性能与当前的Heska和IDEXX临床生物化学分析仪相比较
Randolph M Baral1, Susan M Jaensch2, Douglas A Hayward2
1University of Sydney/Paddington Cat Hospital, Sydney, Australia.
Veterinary clinical pathology
|February 7, 2024
概括
在小动物实践中, Point-of-Care (POC) 生物化学分析仪的性能变化不定. 实现质量目标需要在将POC结果与商业实验室分析仪进行比较时考虑固有的偏差.
科学领域:
- 兽医诊断 兽医诊断 兽医诊断 兽医诊断
- 临床病理学 临床病理学
- 生物化学分析分析的方法
背景情况:
- 照顾点 (POC) 生物化学分析仪是小型动物临床实践的组成部分.
- 这些分析器的独立性能评估很少发生.
研究的目的:
- 为了评估Heska Element DC和IDEXX Catalyst POC分析器的性能.
- 将POC分析器性能与商业实验室分析器 (Cobas 8000) 的性能进行比较.
主要方法:
- 来自121只猫的血样本在POC分析仪和商业分析仪上进行了分析.
- 用布兰德-阿尔特曼差异图来比较结果并评估一致性极限 (LOA).
- 质量目标的评估是基于生物变异和允许的总误差.
主要成果:
- 很少有分析品在POC分析仪上达到严格的质量目标.
- 在不太严格的质量标准下,性能得到了改善.
- 在POC分析仪和商业实验室分析仪之间检测到显著的偏差.
结论:
- 与商业实验室相比,Heska和IDEXX POC分析仪的性能有所不同.
- 实现性能目标需要纠正分析器特定偏差.
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