在患有炎症性肠病的患者中,肌肉衰弱和可能的肉症的高患病率
Ilkay Ergenc1,2, Chasan Ismail Basa3, Alper Uzum3
1Department of Gastroenterology, School of Medicine, Marmara University, Pendik, İstanbul, Turkey.
概括
65岁以下的炎症性肠病 (IBD) 患者通常可能患有肉症,其特征是肌肉强度低. 确诊的肉类是不太常见的,但已经确定了皮质类固醇使用等危险因素.
科学领域:
- 老年学是一门学科.
- 胃肠病学 胃肠病学
- 肌肉骨健康 肌肉骨健康
背景情况:
- 炎症性肠病 (IBD) 影响着大量人口,可能会对肌肉健康产生影响.
- 骨肌肉质量和功能的逐渐丧失,即萨科佩尼亚,在各种患者群体中越来越令人担忧.
- 欧洲老年人肉病工作组 (EWGSOP2) 的标准为诊断肉病提供了一种标准化的方法.
研究的目的:
- 在65岁以下的IBD成年患者中确定可能的肉症和肉症的患病率.
- 在IBD队列中应用EWGSOP2诊断标准来评估肉症.
- 为了确定与IBD患者的肉症相关的潜在风险因素.
主要方法:
- 基于EWGSOP2标准的连续四步算法被用于评估肉症.
- 这包括SARC-F风险调查问卷,手握强度对可能的肉症,肌肉质量的生物阻抗分析,以及严重程度的步行速度.
- 该研究包括129名IBD成年患者和50名年龄和性别匹配的健康对照 (HC).
主要成果:
- 与HC相比,IBD患者的手握强度,步行速度和SARC-F得分明显较低.
- 使用EWGSOP2标准,17.8%的IBD患者患有可能的肉症,6人患有确定的肉症.
- 基于种族的门显示出更高的患病率:34.9%可能的肉症和两个确定的肉症.
- 在过去一年内使用皮质类固醇,晚年和疾病活动是低肌肉强度的独立风险因素.
结论:
- 大约三分之一的65岁以下IBD患者表现出可能的肉症 (肌肉强度低).
- 在这个队列中,确诊的肉类的发病率相对较低.
- 对IBD患者来说,早期识别和管理肉类的危险因素至关重要.
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