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关于开放部分水平喉切除术的瘤结果和预后因素的多中心研究

Eugenia Allegra¹, Maria Rita Bianco¹, Domenico Michele Modica²

¹Department of Health Science, University of Catanzaro, Catanzaro, Italy.

Ear, nose, & throat journal

|February 7, 2024

概括

喉癌的开放性保存手术提供了与全喉切除术相似的生存结果. 这些程序保持喉功能,改善喉癌患者的生活质量.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
手术瘤学手术瘤学

背景情况:

对喉癌的开放性保存手术越来越多地使用.
这些手术的目的是保护喉功能并实现瘤控制.
避免全喉切除术可显著改善患者的生活质量.

研究的目的:

评估开放部分水平喉腔切除术 (OPHL) I和II的瘤学结果.
确定影响喉癌患者生存率和局部失败率的预后因素.

主要方法:

对182名用OPHLs (2005-2015) 治疗的喉平细胞癌患者的回顾性分析.
与接受全喉切除术 (TL) 的队列治疗的生存率的比较 (2004-2014).

主要成果:

在pT2和pT3瘤中,OPHLs和TL之间的疾病特异性存活率没有显著差异.
在pT4瘤,围神经/血管侵袭和OPHL IIb+ARY治疗患者中观察到瘤复发的风险更高.
确定了瘤复发的关键预后因素.

结论:

开放式保存手术是选择喉癌患者的全喉切除术的可行替代方案.
手术方法应考虑瘤特征和患者的病情.
在保持喉功能的同时,OPHL提供了可比的瘤结果.

关键词:

疾病特异性生存率疾病特异性生存率喉癌是一种喉癌.喉的保护喉的保护没有喉切除术的生存率.开放的部分水平喉腔切除术进行全喉切除术.

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