睡眠呼吸暂停和耳之间的关联:一个元分析
Jing Gao1, Ping Tan1, Yunliang Liu2
1Health Medicine Department, The 900th Hospital of the Chinese PLA Joint Logistics Support Force, Fuzhou, Fujian Province, P.R. China.
Ear, nose, & throat journal
|February 7, 2024
概括
睡眠呼吸暂停 (SA) 与成年人耳发病率较高有关. 这种关联与严重的睡眠呼吸暂停特别强烈,这表明需要进一步调查的潜在联系.
科学领域:
- 睡眠医学 睡眠医学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 流行病学 流行病学
背景情况:
- 成年人的睡眠呼吸暂停 (SA) 和耳之间的关系尚未得到充分证实.
- 观察性研究提供了初步证据,需要进行全面的综合.
研究的目的:
- 系统地审查和分析调查睡眠呼吸暂停和 tinnitus 在成年人之间的关联的观察性研究.
- 量化睡眠呼吸暂停的成年人中的耳声的患病率.
主要方法:
- 在主要的科学数据库 (PubMed,Embase,Web of Science等) 中进行系统搜索. 是进行的.
- 包括8项观察性研究 (病例控制或横截面),涉及132,292名成年人.
- 基于异质性的随机效应或固定效应模型被用于元分析.
主要成果:
- 睡眠呼吸暂停与 tinnitus 的明显更高的患病率有关 (OR: 1.65).
- 这种关联对于严重的睡眠呼吸暂停 (OR:2.25) 是显著的,但对于轻度或中度的SA.
- 观察到地理差异,与中国相比,意大利/美国研究的相关性更强.
结论:
- 严重的睡眠呼吸暂停可能是成年人群中耳的重要危险因素.
- 对严重的SA和耳之间联系的机制进行进一步研究是有必要的.
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