相关实验视频
Updated: Jul 4, 2025
09:16
Assessment of Kidney Function in Mouse Models of Glomerular Disease
Published on: June 30, 2018
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在临床诊断中测量尿蛋白
Jesse C Seegmiller1, Lorin M Bachmann2
1Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, United States.
Clinical chemistry
|February 7, 2024
概括
尿中的白蛋白测量是慢性病 (CKD) 监测的关键. 测量程序的显著差异可能会影响CKD诊断和风险分类,突出了标准化的需要.
科学领域:
- 临床化学 临床化学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 生物标志物测量 生物标志物测量
背景情况:
- 尿中的白蛋白测量对于诊断,分类风险和监测慢性病 (CKD) 来说至关重要.
- 临床指南使用尿中的白蛋白与肌素比率 (ACR) 截止值为30和300 mg/g (3和30 mg/mmol).
- 制造商的测量程序之间超过40%的差异可能导致不一致的CKD诊断和风险评估.
结论:
- 尿蛋白测量的标准化对于准确的CKD诊断和风险分层是必不可少的.
- 开发参考系统,包括质谱法和参考材料,对于实现标准化至关重要.
- 需要共同努力,以确保在不同实验室进行一致和可靠的尿蛋白测试.
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