在多层次初级腰部融合后,症状性腰部伪关节炎的预测因素
Hania Shahzad1, Moizzah Ahmad2, Varun K Singh1
1The Ohio State University Wexner Medical Center, 410 W 10th Ave, Columbus, OH, 43210, United States.
North American Spine Society journal
|February 7, 2024
概括
这项研究发现,在脊柱融合手术后,腰椎伪关节炎的发病率为2.70%. 关键预测因素包括维生素D缺乏,骨关节炎,物质使用和以前的脊椎疾病.
科学领域:
- 脊柱外科手术 脊柱外科手术
- 整形外科 整形外科 整形外科
- 健康 结果 研究 研究 结果
背景情况:
- 腰椎脊柱融合是脊柱疾病的常见程序.
- 伪关节炎是腰部融合后的一个重大并发症.
- 了解其发生率和预测因素对于患者护理至关重要.
研究的目的:
- 为了确定腰部融合后伪关节炎的发生率和时间.
- 为了确定人口统计学,并发症和预测伪关节炎的外科手术因素.
- 在10年的时间内分析大量患者队列.
主要方法:
- 从PearlDiver数据库 (2010-2022) 中对保险索赔的回顾性分析.
- 包括76,337名接受多层腰椎脊柱融合的患者.
- 使用千二测试,多变量和Cox生存分析的统计分析.
主要成果:
- 在10年内,2.70%的患者出现了症状性伪关节炎.
- 手术后诊断的平均时间为7.38年.
- 预测因素包括维生素D缺乏,骨关节炎,阿片类药物/NSAID使用,烟草使用和先天性脊柱疾病.
结论:
- 观察到2.70%的症状性腰部伪关节炎的发生率.
- 确定预测因素为风险分层和预防提供了目标.
- 进一步的研究可以优化腰部融合患者的结果和资源配置.
相关概念视频
Appendicitis-I: Introduction
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Herniated Intervertebral Disc l: Introduction
Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Degenerative Disc Disease ll: Pathophysiology
The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...


