非结核性真菌细菌的特征和抗微生物敏感性模式
Abraham J le Roux1, Anneke van der Spoel van Dijk1, Motlatji R B Maloba1
1Department of Medical Microbiology, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.
Southern African journal of infectious diseases
|February 7, 2024
概括
这项研究发现,南非非非结核性真菌菌 (NTM) 隔离物,主要是*Mycobacterium intracellulare*,具有较低的宏化物耐药性. 需要加强监测,以有效管理NTM疾病.
科学领域:
- 医学微生物学 医学微生物学
- 传染性疾病 传染性疾病
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 非结核性真菌菌 (NTM) 感染需要长时间的基于类的治疗.
- 关于南非NTM流行率和宏类耐药性的数据有限.
- 在南非,对NTM进行常规的抗微生物敏感性测试并不是标准实践.
研究的目的:
- 在Tshepong国家卫生实验室服务 (NHLS) 隔离的NTM物种的特征.
- 确定NTM分离物的抗微生物敏感性模式,重点关注宏化物和氨基糖化物.
主要方法:
- 在2020年1月至6月期间收集的194个NTM分离物的回顾性分析.
- 用GenoType® NTM-DR测定对选定的分离物进行物种识别和宏类/氨基糖类耐药性测试.
主要成果:
- * Mycobacterium intracellulare * 是最常见的NTM物种 (67.6%).
- 在2.8%的测试隔离物中检测到宏类耐药性;没有观察到氨基糖化物耐药性.
- 仅在女性患者中发现了耐药性,尽管大多数隔离物来自男性.
结论:
- *M. intracellulare*是这个南非队列中占主导地位的NTM物种.
- 观察到较低的宏类抗药率和缺乏氨基糖化物耐药性.
- 增加NTM监测和耐药性监测对于指导治疗和改善患者结果至关重要.
关键词:
在GenoType® NTM-DR中使用.麦可细菌和鸟类复合体 (Mycobacteria avium complex) 是一个复合体.这种细菌是Mycobacterium abscessus.基因型的抗微生物敏感性没有结核的真菌菌.更多相关视频
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