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Updated: Jul 4, 2025

Studying the Effects of Matrix Stiffness on Cellular Function using Acrylamide-based Hydrogels
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Published on: August 10, 2010

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[细胞外矩阵刚度通过AMPK激活诱导线粒体形态异质性]

Peiyan Duan1, Yi Liu1, Xinyi Lin1

  • 1（ 610041） Institute of Biomedical Engineering, West China School of Basic Medical Sciences and Forensic Medicine, Sichuan University, Chengdu 610041, China.

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
|February 7, 2024
PubMed
概括

细胞外矩阵的刚性会影响人类介质干细胞 (hMSCs) 中的线粒体形状. 更硬的环境激活AMP激活蛋白激酶 (AMPK),导致线粒体的分裂.

关键词:
激活AMPK的激活方式细胞外矩阵刚度 细胞外矩阵刚度裂变和核聚变的发生.线粒体形态学 线粒体形态学干细胞是一种干细胞.

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