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Updated: Jul 4, 2025

Assessing Cellular Target Engagement by SHP2 PTPN11 Phosphatase Inhibitors
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双特异性酸酶1与禁忌素2相互作用,改善线粒体质量控制,防止3型心脏脏综合征

Nanyang Liu1, Yanqiu Ding2, Hao Zhou2

  • 1Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.

International journal of medical sciences
|February 7, 2024
PubMed
概括

双特异性酸酶1 (DUSP1) 在3型心综合征 (CRS-3) 期间保护心脏. 减少DUSP1和破坏DUSP1/PHB2结合会损害线粒体质量控制,导致心脏功能障碍.

关键词:
在CRS-3中使用.这就是DUSP1的原因.在 PHB2 中,我们可以使用 PHB2.线粒体质量控制的质量控制

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