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RNA螺旋酶DDX3调节了Ewing肉瘤中的RAD51定位和DNA损伤修复

Matthew E Randolph1,2, Marwa Afifi3, Aparna Gorthi4

  • 1Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY, USA.

iScience
|February 7, 2024
PubMed
概括

通过控制RAD51定位,RNA螺旋酶DDX3X (DDX3) 通过控制RAD51定位,在尤文肉瘤中独特地影响DNA损伤修复. 抑制DDX3增强了Ewing肉瘤中的辐射敏感性.

关键词:
生物化学 生物化学生物科学 生物科学癌症 癌症 癌症 癌症细胞生物学 细胞生物学分子生物学分子生物学自然科学 自然科学

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