哺乳期母亲的饮食干预会影响母亲便和母乳微生物群
Azhar S Sindi1,2, Lisa F Stinson3, Zoya Gridneva3
1Division of Obstetrics and Gynaecology, School of Medicine, The University of Western Australia, Subiaco, WA 6008, Australia.
Journal of applied microbiology
|February 7, 2024
概括
短期的孕产妇饮食干预显著改变了肠道微生物组和人乳 (HM) 微生物组的组成. 这些变化在饮食结束后持续了数周,影响了关键的细菌物种.
科学领域:
- 微生物组研究的研究.
- 母婴健康 孕产妇和婴儿健康
- 营养科学 营养科学
背景情况:
- 母亲的微生物组在婴儿的发育和健康中起着至关重要的作用.
- 哺乳期的饮食干预可能会影响母婴微生物组合.
- 了解这些影响对于促进健康婴儿肠道殖民至关重要.
研究的目的:
- 为了研究为期两周的孕产妇饮食干预对便和人乳 (HM) 微生物群的影响.
- 为了评估细菌组成的变化,减少脂肪和糖,增加纤维的饮食.
- 为了确定这些饮食对母亲微生物组的影响的持续时间.
主要方法:
- 一项试点研究涉及11名接受为期两周的饮食干预的母亲.
- 使用全长16S rRNA基因测序对母体便和母乳 (HM) 样本进行分析.
- 在基线和干预期间评估母亲的宏观营养素摄入量.
主要成果:
- 饮食干预显著降低了母亲的脂肪和糖摄入量.
- 观察到母亲便微生物组合的显著变化,包括Bacteroides caccae和Faecalibacillus intestinalis的变化.
- 人类牛奶 (HM) 微生物组显示,Cutibacterium acnes显著增加,Haemophilus parainfluenzae显著减少.
- 微生物组的变化持续了干预后长达8周.
结论:
- 哺乳期的短期母亲饮食修改可以有效地改变母体便和人乳 (HM) 微生物组的组成.
- 观察到的微生物组变化表明,母亲的微生物组对饮食变化的敏感性.
- 这些发现强调了饮食策略可能对母亲的微生物群产生积极影响的潜力,从而影响婴儿的肠道健康.
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