在缺血性和非缺血性扩展性心肌病中的MRI特征追踪中左心房应变的预后效用:一个多中心研究
Fai Wang Fong1, Subin Hwang1, Yueyi Xu1
1Department of Diagnostic Radiology, The University of Hong Kong, Rm 406, Block K, Queen Mary Hospital, 102 Pokfulam Rd, Hong Kong SAR.
AJR. American journal of roentgenology
|February 7, 2024
概括
从心脏MRI获得的左心房应变 (LAS) 参数在扩张性心肌病 (DCM) 患者中比传统标志物具有更高的预后价值. LAS 水库和管道显著预测结果,改善患者风险分层.
科学领域:
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
- 医疗成像医学成像
背景情况:
- 心脏MRI对于扩张性心肌病 (DCM) 的预后评估至关重要.
- 传统的标志物包括晚期加多增强 (LGE) 和左心室全球纵向菌株 (LVGLS).
- 左心房应变 (LAS) 参数 (储体,管道,助推器) 显示出潜在的预后作用.
研究的目的:
- 在DCM患者中评估MRI特征跟踪 (FT) 衍生LAS参数的预后效用.
- 将LAS参数的预后值与LGE和LVGLS进行比较.
- 评估患有缺血性或非缺血性DCM的患者.
主要方法:
- 从五个中心对811名DCM患者进行了回顾性分析.
- 从电影图像中测量FT衍生的LAS参数和LVGLS.
- 量化LGE和综合结果的评估 (所有原因死亡率或心力衰竭住院治疗).
- 进行了多变量考克斯回归和卡普兰-梅尔分析.
主要成果:
- LAS 水库和管道是不良结果的显著独立预测因素.
- LAS参数显示出比LVGLS和LGE更大的预后效用.
- 有不良结局的患者LAS水库和导管值较小.
- 在多变量模型中,LGE和LAS助推器不是显著的独立预测因素.
结论:
- 来自MRI的LAS水库和导管是DCM中显著的独立预后标志物.
- 拉斯分析提供了超越传统标记的增量预后信息.
- 由FT衍生的LAS参数增强了DCM患者的风险分层.
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