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天然深层菌溶剂的抗菌和抗真菌活动
Hadeer M Bedair1, Tamer M Samir1, Fotouh R Mansour2
1Department of Microbiology and Immunology, Faculty of Pharmacy, Misr University for Science and Technology (MUST), Giza, 12566, Egypt.
Applied microbiology and biotechnology
|February 7, 2024
概括
由于微生物耐药性增加,天然深层菌溶剂 (NADES) 显示出作为常规抗生素替代品的显著前景. 本次审查强调了它们的抗菌和抗真菌活性,提供了对抗感染的可持续方法.
科学领域:
- 绿色化学 绿色化学
- 微生物学 微生物学
- 药理学 药理学是指药理学的学科.
背景情况:
- 抗生素耐药性的增加构成了全球公共卫生威胁,迫使人们探索新型抗菌剂.
- 深度环氧溶剂 (DESs),特别是那些来自自然来源的溶剂 (NADESs),正在成为可持续的替代品,具有有利的特性,如低波动性和成本效益.
- NADES与自然产品的趋势以及对合成化合物的减少依赖相一致.
研究的目的:
- 审查和讨论各种天然深层乳化溶剂 (NADES) 的抗菌性质,包括抗菌和抗真菌活性.
- 建立NADES作为传统抗生素可行的替代品,以应对耐药性问题.
- 介绍第一个关于NADESs抗菌应用的综合文献调查.
主要方法:
- 对研究研究NADESs的抗菌作用的文献综述.
- 对各种微生物报告的抗菌和抗真菌活性进行分析.
- 纳德斯的合成方法包括加热,冷干燥,蒸发,研磨和辅助技术 (超声波,微波).
主要成果:
- 纳德斯显示出作为抗菌剂对一系列微生物的显著潜力.
- 该审查确定了与各种NADES配方相关的大量抗菌和抗真菌活性.
- NADESs在克服现有的细菌耐药机制方面表现有前途.
结论:
- 天然深层菌溶剂 (NADES) 是传统抗生素的一个有希望和可持续的替代品.
- NADES 具有显著的抗菌和抗真菌特性,为抗微生物耐药性提供了潜在的解决方案.
- 对NADES的进一步研究可能会导致对抗耐药性病原体的新治疗策略的开发.
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